Best Practices for the Design of Large-Scale Services on Windows Azure Cloud Services

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This MSDN article authored by Mark Simms and Michael Thomassy provides thoughtful guidance based on real-world customer scenarios for building scalable applications on Windows Azure and SQL Database, leveraging the Platform-as-a-Service (PaaS) approach (such applications are built as Windows Azure Cloud Services, using web and worker roles).

Another related article I’d recommend is “On Designing and Deploying Internet-Scale Services” by James Hamilton.