The Hyper-V documentation team recently released the Virtualization Fabric Design Considerations Guide.
You can download this document here: http://gallery.technet.microsoft.com/Virtualization-Fabric-e9402b76
This guide details a series of steps and tasks that you can go through to design a virtualization fabric that is able to host many virtual machines. Although all virtualization fabrics contain storage and servers for hosting virtual machines, in addition to the networks that connect them, every organization’s virtualization fabric design will likely be different. Throughout the steps and tasks, the guide presents the relevant design and configuration options available to you to meet functional and service quality (such as availability, scalability, performance, manageability, and security) requirements.
Please look it over – and let us know if you have any feedback!