The 7th Guest under Virtual PC
Released in 1993 - The 7th Guest was one of the first CD-ROM based games I ever played (on a friend's 1x CD-ROM drive which was a caddy loader). This was the first of the infamous 'interactive movie' games. It places you in a creepy house built by an insane toymaker - and has you solve a number of little puzzles - with a slowly evolving and definitely twisted story line:
This game is 'playable' under Virtual PC. The sound is not the greatest - and the video jerks here and there - but the game is still completable. It should automatically detect the correct settings to use when installed under straight DOS - I had some problems with the mouse when I tried to run it under a Windows 98 virtual machine.
Cheers,
Ben