SPSite: The Web application could not be found

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You’re trying to use the SharePoint 2010 server side API’s but you’re getting the exception:

The Web application at https://... could not be found. Verify that you have typed the URL correctly. If the URL should be serving existing content, the system administrator may need to add a new request URL mapping to the intended application.

Then the root cause is probably not:

-Misconfigured AAM
-Missing App. Pool permissions

It is probably that you’re compiling for x86 platform target.

Change that to x64 and your code will probably work:

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-thomas