If you are looking for a fix for the widely reported security issue a via malicious USB drive, or remotely via network shares and WebDAV then check out the link below.
“To implement the workaround that disables .LNK and .PIF file functionality automatically on a computer that is running Windows XP, Windows Server 2003, Windows Vista, Windows Server 2008, Windows 7, or Windows Server R2 click the Fix this problem link under Enable workaround. To undo the workaround, click the Fix this problem link under Disable workaround. In either scenario, click Run in the File Download dialog box, and follow the steps in the Fix it wizard.
NOTE: Applying the Fix it will require a restart of the machine. The installation of the Fix it will prompt the user before restarting the system. Enterprise deployments allows for unattended install with the following Display options”
Please do read the entire advisory as there is alot of information in there that you need to read before applying the fix it.
For more info as well check out http://www.microsoft.com/technet/security/advisory/2286198.mspx
As always keep you anti-virus software up todate to help ward off any known issues.