Confronting Global Grand Challenges

On March 12 and 13, I had the privilege of joining with more than 450 leading thinkers drawn from around the world and across disciplines at the inaugural Global Grand Challenges Summit in London. Organized by the UK’s Royal Academy of Engineering in partnership with the US National Academy of Engineering and the Chinese Academy…


On World AIDS Day, HIV Research Provides a Ray of Hope

The first documented case of HIV was in 1981. Today, HIV is viewed as a treatable, chronic disease by many in developed nations where treatments are readily available. Yet HIV continues to devastate, claiming the lives of 1.8 million people annually—about 5,000 deaths per day. Those fortunate enough to have access to treatment must arrange…


Understanding the Immune Response to HIV

HIV infection may not be the death sentence it once was, but it remains an undeniably serious condition that requires aggressive, life-long treatment and entails the ever-present threat of severe immunological impairment. Consequently, medical researchers continue to investigate the mechanisms by which HIV infection evades detection by the body’s normal immune responses. In the August…


Celebrating Richard Feynman at TEDxCaltech

One of the responsibilities for us as researchers is to have the courage to challenge accepted “truths” and to seek out new insights. Richard Feynman was a physicist who not only epitomized both of these qualities in his research but also took enormous pleasure in communicating the ideas of physics to students. Feynman won the…


Fighting HIV and AIDS — Journal of Experimental Medicine

Two Microsoft researchers, Jonathan Carlson and David Heckerman, working with two teams of HIV researchers at the Ragon Institute of MGH, MIT, and Harvard, and at the University of Alabama have identified new findings that could help in the fight against HIV and AIDS.  Their results appear in back-to-back articles just released in the Journal…