Orcas Beta 2 Automation Planning

I am in the process of finalizing the C# automation matrix for Beta 2. One of the scenarios that I feel receives very little coverage today, and that I would like some help with, is the interaction of Visual Studio with other software or machine configurations.

Have there been any pain points that you have run into when attempting to use Visual Studio in the past or install it that we could have made better? How is your dev box configured? Do you run as an admin or normal user? What about on Vista? Have you ever needed to install VS on a domain controller? What about a server in a DMZ that is seeing an issue that is not reproducible in the dev environment?

Anyway... let me know your thoughts and I'll see what I can do in order to incorporate this into our testing somehow.

Are there things that you would like to hear about from the C# testing/automation perspective?