The book covers everything you need to know to get started with writing professional software components with F#, especially in enterprise or Silverlight-oriented situations. The inclusion of complete worked samples such as "Forecast'r - the world's simplest weather forecast site" really gives a picture of how F# can add up end-to-end for a software problem, and a chapter devoted to Silverlight will help you unlock the use of F# in full-featured client-side programming. The "Applications" part of the book covers C#, Databases, XML, ASP.NET MVC, Silverlight and Services.
One thing that really pleases me is the simplicity and clarity of the presentation of the basics of the language, succinctly and clearly, In 400 pages the book contains a lot of useful information.
Congratulations to Ted, Aaron, Talbott and Rick for a fine job on this book. I know a huge amount of love and energy went into it.