Stephen Toulouse (affectionately known as Stepto around MS) is being interviewed on Channel 9 this week. Stepto is on the front lines of Microsoft's security response effort, so these interviews should be good.
Stephen Toulouse - Introduction to Microsoft's security response center
Stephen Toulouse is a security program manager with Microsoft's security response center. The security response center is the team (and place) that goes into action when a new vulnerability or attack on one of Microsoft's products or customers is found and reported to firstname.lastname@example.org.