Last night I started getting calls last night from friends whose computers were infected by the Blaster worm. It ain't fun! If you haven't patched your OS yet, now is a good time... By late evening yesterday a friend's NT4 box was being probed (port 135) about 6 times a minute. Each time it happened his system crashed, so he wasn't getting much work done.
And if you are already infected, you can get a removal tool from http://www.symantec.com/avcenter/tools.list.html.
[Updated] Just a tip for those of you who are getting hit a lot and having your box rebooted before you can install the patch: To stop those pesky reboots try “shutdown